BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The part of the enzyme where the substrate binds is called the active site (since that’s where the catalytic “action” happens). A substrate enters the active site of the enzyme. This forms the enzyme-substrate complex.

Detailed explanation-2: -Active sites are regions usually on the surface of enzymes specially modelled by nature during evolution that either catalyse a reaction or are responsible for substrate binding. The active site can be, therefore, divided into two parts, which include the catalytic site and the substrate binding site (1).

Detailed explanation-3: -Active site is a region on an enzyme to which the substrates of a chemical reaction bind in order to undergo a catalyzed chemical reaction whereas binding site is a region on a protein, DNA or RNA, to which ligands can bind. This is the key difference between active site and binding site.