BIOMOLECULES AND ENZYMES

Detailed explanation-1: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-2: -What denatures enzymes? There are two main causes for enzyme denaturation: temperature and pH. Enzymes function best at the optimal temperature of an organism.

Detailed explanation-3: -Chemical induced denaturation Chemical denaturation of the enzyme was performed with increasing concentrations of the denaturant at pH 4.0.

Detailed explanation-4: -Changes in pH can disrupt the weak interactions that hold proteins together (The H+ and OH-ions can interfere with intermolecular bonds that hold the enzyme together. Changes in pH can cause an enzyme to denature (lose their precise shape) and the substrate won’t fit into the active site.