BIOMOLECULES AND ENZYMES

BIOLOGY

ENZYMES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What happens to an enzyme when its active site changes shape irreversibly?
A
It is killed
B
It is denatured
C
It is diffused
D
None of the above
Explanation: 

Detailed explanation-1: -The shape of the active site will change irreversibly, and it will no longer be able to bind to its substrate. The enzyme is said to be denatured, or we say that denaturation has occurred. This results in the decrease in rate, or stopping, of the reaction.

Detailed explanation-2: -When an enzyme denatures, its active site changes its shape, as you can see in this diagram. This is because the protein structure of the enzyme has changed. You might notice that the active site is no longer a complementary shape to a specific substrate molecule.

Detailed explanation-3: -Denaturation is caused by the breaking of the bonds that hold the enzyme together in its three-dimensional shape. Heat can break hydrogen and ionic bonds, which disrupts the shape of the enzyme and will change the shape of the active site.

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