BIOMOLECULES AND ENZYMES

Detailed explanation-1: -A denatured enzyme refers to an enzyme that has lost its normal three-dimensional, or tertiary, structure. Once an enzyme loses this structure and is denatured, it is no longer able to function. Therefore, any catalytic advantage is lost, and the biological reaction no longer proceeds at an increased rate.

Detailed explanation-2: -This is because the protein structure of the enzyme has changed. You might notice that the active site is no longer a complementary shape to a specific substrate molecule. This means that the substrate cannot bind to the active site anymore. And this denatured enzyme can no longer catalyze enzyme-controlled reactions.

Detailed explanation-3: -Denaturation of enzymes causes bonds to be broken, structure to be disrupted and it stops functioning. This happens to enzymes when they are exposed to extreme, unsuitable conditions, for instance, high temperatures or extreme pH levels.