BIOMOLECULES AND ENZYMES

Detailed explanation-1: -What denatures enzymes? There are two main causes for enzyme denaturation: temperature and pH. Enzymes function best at the optimal temperature of an organism.

Detailed explanation-2: -Although many native proteins are resistant to the action of the enzyme trypsin, which breaks down proteins during digestion, they are hydrolyzed by the same enzyme after denaturation. The peptide bonds that can be split by trypsin are inaccessible in the native proteins but become accessible during denaturation.

Detailed explanation-3: -Enzyme structures unfold (denature) when heated or exposed to chemical denaturants and this disruption to the structure typically causes a loss of activity. Protein folding is key to whether a globular protein or a membrane protein can do its job correctly.