BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Steroid hormone receptors are found on the plasma membrane, in the cytosol and also in the nucleus of target cells. They are generally intracellular receptors (cytoplasmic) and initiate signal transduction for steroid hormones, which lead to changes in gene expression over a time period of hours to days.

Detailed explanation-2: -Steroid hormones bind receptors in the cell nucleus and in the cell membrane. The most widely studied class of steroid hormone receptors are the nuclear receptors, named for their function as ligand-dependent transcription factors in the cell nucleus.

Detailed explanation-3: -Steroid hormone receptors are members of the ligand-activated nuclear receptor superfamily. These receptors bind to specific consensus DNA sequences called hormone response elements and exert control of gene expression either in a stimulatory or inhibitory fashion (1).

Detailed explanation-4: -Recent studies suggest that steroid hormones use receptors on cellular membranes both to gain access to the intracellular compartment and to modulate cellular functions. These interactions with cell-surface receptors have important physiological consequences.