BIOMOLECULES AND ENZYMES

Detailed explanation-1: -THE STOMACH Two major forms of gastrin exist, gastrin-34 (G34, composed of 34 amino acids) and gastrin-17 (G17, composed of 17 amino acids). In humans, over 90% of the gastrin present in the antral mucosa is the G17 form.

Detailed explanation-2: -Big gastrin (G34) is one form of gastrin predominate in circulation after a meal, another major form is called little gastrin (G17). Both forms of gastrin have been isolated from human gastrinoma and hog antral mucosa. G34 is carboxy-amidated and can be sulphated or unsulphated at the tyrosine residues.

Detailed explanation-3: -Abnormal gastrin production occurs in some clinical and diseased states, a condition known as hypergastrinemia and defined by a Gastrin level greater than 100–150 pg/ml [2].

Detailed explanation-4: -Gastrin is a hormone produced by the stomach, which stimulates gastric motility and the release of gastric acid.