BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Ketone bodies are derived from oxidation of nonesterified or free fatty acids (FFAs) by the liver and are used as an energy source by many tissues during periods of glucose deficiency. FFAs released from adipose tissue are assimilated by the liver at a rate dependent on their plasma concentration.

Detailed explanation-2: -Ketones in themselves are breakdown products of fatty acid metabolism. When fat is used as an energy source it is converted into ketones in the liver by a process called ketogenesis. First, free fatty acids are released and converted into acetyl CoA, via beta oxidation in the liver’s mitochondria.

Detailed explanation-3: -Ketone bodies are produced by the liver and used peripherally as an energy source when glucose is not readily available. The two main ketone bodies are acetoacetate (AcAc) and 3-beta-hydroxybutyrate (3HB), while acetone is the third, and least abundant, ketone body.