BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Corticotropin-releasing hormone (CRH) is released from the hypothalamus, which stimulates the anterior pituitary to release adrenocorticotropic hormone (ACTH).

Detailed explanation-2: -Aldosterone is controlled by the renin-angiotensin system, while the rest of the adrenal glands’ hormone production is controlled by adrenocorticotropic hormone (ACTH).

Detailed explanation-3: -ACTH is also reported to stimulate aldosterone secretion, although its effects on aldosterone under normal conditions are mild compared with those of AII and potassium (1). Primary aldosteronism (PA) is a major cause of secondary hypertension, affecting 5–10% of all hypertensive patients (2, 3, 4).

Detailed explanation-4: -High levels of serum potassium directly stimulate aldosterone secretion from the zona glomerulosa. An increase in dietary potassium induces an increase in aldosterone secretion, whereas potassium depletion causes a decrease.

Detailed explanation-5: -Adrenocorticotropic hormone (ACTH) is a hormone your pituitary gland releases that plays a large role in how your body responds to stress. The release of ACTH triggers your adrenal glands to produce cortisol, the “stress hormone, ” and androgens (a group of sex hormones).