BIOLOGY
HORMONES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Acetylcholine act by cAMP pathway
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Gastrin act by cAMP pathway
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Hitamine act by PIP2 pathway
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Histamine act by cAMP pathway
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Detailed explanation-1: -The correct option is b. Histamine is present in almost all tissues of the human body. It is mainly stored in the granules of mast cells.
Detailed explanation-2: -Answer and Explanation: Of the given statements about histamines the one that is not correct is that it is a bronchodilator.
Detailed explanation-3: -Histamine has diverse effects, both pro-inflammatory and anti-inflammatory, which are determined by both the histamine receptor subtype and the cells stimulated types (38).
Detailed explanation-4: -We conclude that the canonical beta-catenin pathway acts downstream of the histamine receptor H1 in a variety of cell types. The observation that inflammatory molecules, like histamine, activate the beta-catenin pathway may provide a molecular explanation for a possible link between inflammation and cancer.