BIOLOGY
NUCLEIC ACIDS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The hormones in the blood are changed by increased differences in genes
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The protein coded by the DNA has a different amino acid sequence
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The carbohydrate coded by the DNA has a different structure
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The chromosome carrying this gene changes shape during cell reproduction
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Detailed explanation-1: -Sickle cell disease (SCD) is characterized by a single point mutation in the seventh codon of the -globin gene. Site-specific correction of the sickle mutation in hematopoietic stem cells would allow for permanent production of normal red blood cells.
Detailed explanation-2: -Sickle cell disease (SCD) is a genetic disorder caused by a mutation in both copies of a person’s HBB gene. This gene encodes a component of hemoglobin, the oxygen-carrying protein in red blood cells. The mutation causes hemoglobin molecules to stick together, creating sickle-shaped red blood cells.
Detailed explanation-3: -Sickle cell anemia is an example of a genetic disease caused by a point mutation.
Detailed explanation-4: -Sickle cell disease is caused by a mutation in the hemoglobin-Beta gene found on chromosome 11. Hemoglobin transports oxygen from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) are smooth and round and glide through blood vessels.