BIOMOLECULES AND ENZYMES

BIOLOGY

NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
DNA is more stable because its pentose sugar has a ____ on the 2’ carbon, unlike ribose.
A
Hydrogen (H)
B
Hydrogen ion (H+)
C
Hydroxyl group (OH)
D
Carboxyl group (COOH)
E
Phosphate group (PO4)
Explanation: 

Detailed explanation-1: -Due to its deoxyribose sugar, which contains one less oxygen-containing hydroxyl group, DNA is a more stable molecule than RNA, which is useful for a molecule which has the task of keeping genetic information safe. RNA, containing a ribose sugar, is more reactive than DNA and is not stable in alkaline conditions.

Detailed explanation-2: -Why DNA is more stable than RNA? DNA molecules are much more stable because they are double stranded throughout their length and enzymes are normally present in the nucleus to repair damage to DNA. RNA molecules must be continuously replaced as they are being broken down at various rates.

Detailed explanation-3: -Two types of pentose are found in nucleotides, deoxyribose (found in DNA) and ribose (found in RNA). Deoxyribose is similar in structure to ribose, but it has an-H instead of an-OH at the 2′ position.

Detailed explanation-4: -The more stable form of DNA helix is conformation. The conformation of DNA helix depends on the hydration level, DNA sequence, the amount and direction of supercoiling, chemical modifications of the bases. X-ray diffraction shows that conformation is highly hydrated thus DNA is stable in conformation.

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