BIOMOLECULES AND ENZYMES

Detailed explanation-1: -An -helix is a right-handed coil of amino-acid residues on a polypeptide chain, typically ranging between 4 and 40 residues. This coil is held together by hydrogen bonds between the oxygen of C=O. on top coil and the hydrogen of N-H on the bottom coil.

Detailed explanation-2: -Secondary structure refers to regular, recurring arrangements in space of adjacent amino acid residues in a polypeptide chain. It is maintained by hydrogen bonds between amide hydrogens and carbonyl oxygens of the peptide backbone. The major secondary structures are -helices and -structures.

Detailed explanation-3: -Within a protein, multiple amino acids are linked together by peptide bonds, thereby forming a long chain. Peptide bonds are formed by a biochemical reaction that extracts a water molecule as it joins the amino group of one amino acid to the carboxyl group of a neighboring amino acid.

Detailed explanation-4: -Hydrogen bonds between polar amine and carboxyl groups alleviate the desolvation penalty of those groups as they become buried in protein’s native structure. This, in turn, gives rise to the familiar protein secondary structures, such as alpha-helices and beta-sheets.

Detailed explanation-5: -While secondary structure is created solely by hydrogen bonding between the N-H and C=O. groups on the amino acid chain backbone, the tertiary structure is determined by interactions of amino acid R-groups (also known as side chains), with other R-groups and the environment.