BIOMOLECULES AND ENZYMES

BIOLOGY

NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The joining of two adjacent nucleotide in DNA strand is by:
A
Peptide bond
B
Hydrogen bond
C
Phosphodiester bond
D
Glycosidic bond
Explanation: 

Detailed explanation-1: -DNA is a polymer of nucleotides which are linked to each other by 3-5 phosphodiester bond.

Detailed explanation-2: -The bond joining two successive nucleotides in the same strand of DNA is called the phosphodiester bond. the phosphodiester bond is the linkage between the 3’ carbon atom of one sugar molecule and the 5’ carbon atom of another, deoxyribose in DNA and ribose in RNA.

Detailed explanation-3: -Adjacent nucleotides of a single strand of DNA are joined by covalent bonds called phosphodiester bonds.

Detailed explanation-4: -When nucleotides are incorporated into DNA, adjacent nucleotides are linked by a phosphodiester bond: a covalent bond is formed between the 5’ phosphate group of one nucleotide and the 3’-OH group of another (see below). In this manner, each strand of DNA has a “backbone” of phosphate-sugar-phosphate-sugar-phosphate.

Detailed explanation-5: -Specifically, the phosphodiester bond links the 3’ carbon atom of one sugar molecule and the 5’ carbon atom of another (hence the name, 3’, 5’ phosphodiester linkage). These saccharide groups are derived from deoxyribose in DNA and ribose in RNA. Phosphodiesters are negatively charged at pH 7.

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