BIOLOGY
NUCLEIC ACIDS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Denaturation
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Renaturation
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Activation
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Dehydration
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Detailed explanation-1: -denaturation, in biology, process modifying the molecular structure of a protein. Denaturation involves the breaking of many of the weak linkages, or bonds (e.g., hydrogen bonds), within a protein molecule that are responsible for the highly ordered structure of the protein in its natural (native) state.
Detailed explanation-2: -During the denaturation of proteins, the secondary and tertiary structures get destroyed and only the primary structure is retained. Covalent bonds are broken and interaction between amino-acid chains gets disrupted. This results in the loss of biological activity of the proteins.
Detailed explanation-3: -Denaturation breaks the intramolecular bonds, such as hydrogen bonds and van der Waals interactions, that hold the protein in its three-dimensional shape. Without the proper shape, the protein cannot function.
Detailed explanation-4: -If the temperature or pH of a protein’s environment is changed, or if it is exposed to chemicals, these interactions may be disrupted, causing the protein to lose its three-dimensional structure and turn back into an unstructured string of amino acids.