BIOMOLECULES AND ENZYMES

BIOLOGY

NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is helicase?
A
this enzyme unzips the DNA double helix
B
This molecule is double-stranded
C
This molecule is single-stranded
D
None of the above
Explanation: 

Detailed explanation-1: -Helicases are enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes. There are DNA and RNA helicases. DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands allowing each strand to be copied.

Detailed explanation-2: -Key enzyme involved in DNA replication, it is responsible for ‘unzipping’ the double helix structure by breaking the hydrogen bonds between bases on opposite strands of the DNA molecule.

Detailed explanation-3: -Helicases are essential enzymes involved in all aspects of nucleic acid metabolism including DNA replication, repair, recombination, transcription, ribosome biogenesis and RNA processing, translation, and decay.

Detailed explanation-4: -The main enzyme that unwinds DNA, is DNA helicase. Helicase “unzips” DNA in order to kickstart DNA replication. Helicase action requires energy in the form of adenosine triphosphate (ATP). Helicase is hexameric in structure, which means it resembles a ring with 6 sides.

Detailed explanation-5: -This separated, independent structure with all base pairs unzipped is called ssDNA. The DNA unzipping and the DNA unwinding result in a structural transformation from dsDNA to ssDNA.

There is 1 question to complete.