BIOMOLECULES AND ENZYMES

BIOLOGY

NUCLEIC ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following describes a DNA strand that would be most stable at high temperatures?
A
25% A/T and 75% C/G
B
50% A/T and 50% C/G
C
75% A/T and 25% C/G
D
100% A/T and 0% C/G
Explanation: 

Detailed explanation-1: -A DNA molecule consisting only of guanines and cytosines is much more stable and melts around or above 100°C depending on the concentration of NaCl.

Detailed explanation-2: -The helical structure of double-stranded DNA is destabilized by increasing temperature. Above a critical temperature (the melting temperature), the two strands in duplex DNA become fully separated.

Detailed explanation-3: -The stability of the DNA double helix depends on a fine balance of interactions including hydrogen bonds between bases, hydrogen bonds between bases and surrounding water molecules, and base-stacking interactions between adjacent bases.

Detailed explanation-4: -Because G:C pairs have an additional hydrogen bond than A:T pairs, the GC-rich genomes are expected to be thermally more stable in high-temperature environments [23].

There is 1 question to complete.