BIOLOGY
NUCLEIC ACIDS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is the convention used to specify the sequence of bases in DNA?
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We start at the 3’ end.
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We start at the end closest to the first thymine.
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We start at the end closest to the first adenine.
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We start at the 5’ end.
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Explanation:
Detailed explanation-1: -By convention, sequences are usually presented from the 5’ end to the 3’ end. For DNA, the sense strand is used.
Detailed explanation-2: -The 5′-end (pronounced “five prime end") designates the end of the DNA or RNA strand that has the fifth carbon in the sugar-ring of the deoxyribose or ribose at its terminus.
Detailed explanation-3: -A nucleic acid strand is inherently directional, and the “5 prime end” has a free hydroxyl (or phosphate) on a 5’ carbon and the “3 prime end” has a free hydroxyl (or phosphate) on a 3’ carbon (carbon atoms in the sugar ring are numbered from 1’ to 5’; ).
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