BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Denaturation can also be caused by changes in the pH which can affect the chemistry of the amino acids and their residues.

Detailed explanation-2: -Proteins change their shape when exposed to different pH or temperatures. The body strictly regulates pH and temperature to prevent proteins such as enzymes from denaturing. Some proteins can refold after denaturation while others cannot. Chaperone proteins help some proteins fold into the correct shape.

Detailed explanation-3: -denaturation, in biology, process modifying the molecular structure of a protein. Denaturation involves the breaking of many of the weak linkages, or bonds (e.g., hydrogen bonds), within a protein molecule that are responsible for the highly ordered structure of the protein in its natural (native) state.

Detailed explanation-4: -Higher temperature and extreme pH may cause a protein to lose its structure and makes it inactive.

Detailed explanation-5: -As a result of denaturation, globules get unfolded and helixes get uncoiled. Secondary and tertiary structures of protein are destroyed, but the primary structures remain unaltered. It can be said that during denaturation, secondary and tertiary-structured proteins get converted into primary-structured proteins.