BIOMOLECULES AND ENZYMES

BIOLOGY

PROTEINS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Proline and hydroxyproline are amino acids?
A
Yes
B
Yes, because of its amino group
C
No, are imino acids
D
No, are proteins
Explanation: 

Detailed explanation-1: -S2: Proline and hydroxyproline are imino acids, not amino acids. An imino acid is a compound that has an imino group and a carboxylic acid group. An imino group is when nitrogen is double bonded to a carbon atom and single bonded to either a hydrogen atom or an sp3-hybridized carbon atom.

Detailed explanation-2: -Proline is formally NOT an amino acid, but an imino acid. Nonetheless, it is called an amino acid. The primary amine on the carbon of glutamate semialdehyde forms a Schiff base with the aldehyde which is then reduced, yielding proline.

Detailed explanation-3: -Proline and hydroxyproline contains an -imino group and, therefore, they are -imino acids (Fig.

Detailed explanation-4: -Quick Reference. An acid derived from an imine in which the nitrogen of the imino group and the carboxyl group are attached to the same carbon atom. Proline and hydroxyproline are imino acids, normally classified with amino acids.

Detailed explanation-5: -Proline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver; it does not have to be obtained directly through the diet. Proline is the precursor to hydroxyproline, which is a major amino acid found in the connective tissue of the body – collagen.

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