BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The stability of the collagen fibril is reinforced by hydrogen bonds that involve the hydroxyl groups of hydroxy-proline and hydroxylysine residues in the chains. These hydrogen bonds form crosslinks both within and between the individual collagen molecules in a fibril.

Detailed explanation-2: -The defining feature of collagen is an elegant structural motif in which three parallel polypeptide strands in a left-handed, polyproline II-type (PPII) helical conformation coil about each other with a one-residue stagger to form a right-handed triple helix (Figure 1).

Detailed explanation-3: -The protein collagen is the main component of human skin. It has unique properties: it remains soft and flexible under low stress and stiffens when stress is increased. FAU researchers have now discovered the mechanisms that cause collagen’s mechanical stiffness to adapt to external stress.

Detailed explanation-4: -Type I collagen is the most abundant collagen found in connective tissues including skin, tendon, and bone tissue. It is the major component and the primary determinant of tensile strength of the ECM.