BIOLOGY
PROTEINS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The unique shape of prolineaids the formation of
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Prolinehas a distinctive cyclic side chain giving it exceptional rigidity
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Prolineis important for the formation of
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The geometrical shape of prolinedisrupts the secondary structures of
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Detailed explanation-1: -Proline is unique in that it is the only amino acid where the side chain is connected to the protein backbone twice, forming a five-membered nitrogen-containing ring.
Detailed explanation-2: -When proline is in a peptide bond, it does not have a hydrogen on the amino group, so it cannot donate a hydrogen bond to stabilize an helix or a sheet. It is often said, inaccurately, that proline cannot exist in an helix.
Detailed explanation-3: -Proline is unique among the standard amino acids in that it does not have both free -amino and free -carboxyl groups. Instead, its side chain forms a cyclic structure as the nitrogen atom of proline is linked to two carbon atoms.
Detailed explanation-4: -The statement that is not true is choice (C) Involve the R-groups. The hydrogen bonding of alpha-helix does not depend on the R-group or side chains of the amino acids. It only involves the hydrogen bonding between the peptide bonds in the protein.