BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Due to changes in temperature, pH, or other chemical activities, denaturation of protein molecules occur. In many situations, denaturation is reversible. Proteins can not regain their native structure until the denaturing agent is removed.

Detailed explanation-2: -In many cases, denaturation is reversible. Since the primary structure of protein is intact, once the denaturing influence is removed, proteins can regain their native state by folding back to the original conformation. This process is called renaturation.

Detailed explanation-3: -In many cases, denaturation is reversible (the proteins can regain their native state when the denaturing influence is removed). This process can be called renaturation.

Detailed explanation-4: -Enzyme denaturation is the process in which the conformational change of protein structure occurs in response to a denaturing agent. The result is the active site’s conformation is altered and the activity of the enzyme is lost. No, a denatured enzyme cannot be renatured.

Detailed explanation-5: -Protein denaturation is said to be irreversible when the denatured state achieved by increasing temperature or by using chemical denaturants is unable to return to the native, biologically functional state upon removal of the factor that caused denaturation.