BIOMOLECULES AND ENZYMES

BIOLOGY

STRUCTURE OF PROTEINS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What happens to an enzyme when it is denatured?
A
Activation energy is lowered.
B
It becomes stronger.
C
It loses its shape.
D
Activation energy is raised.
Explanation: 

Detailed explanation-1: -Denaturation of enzymes causes bonds to be broken, structure to be disrupted and it stops functioning. This happens to enzymes when they are exposed to extreme, unsuitable conditions, for instance, high temperatures or extreme pH levels.

Detailed explanation-2: -A denatured enzyme refers to an enzyme that has lost its normal three-dimensional, or tertiary, structure. Once an enzyme loses this structure and is denatured, it is no longer able to function. Therefore, any catalytic advantage is lost, and the biological reaction no longer proceeds at an increased rate.

Detailed explanation-3: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-4: -When an enzyme denatures, its active site changes its shape, as you can see in this diagram. This is because the protein structure of the enzyme has changed. You might notice that the active site is no longer a complementary shape to a specific substrate molecule.

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