BIOMOLECULES AND ENZYMES

Detailed explanation-1: -A synthetic vitamin K precursor called menadione (vitamin K3) is used as a vitamin supplement. First recognized in 1929, the vitamin was isolated and analyzed structurally in 1939 by Danish biochemist Henrik Dam. A deficiency of vitamin K in the body leads to an increase in clotting time of the blood.

Detailed explanation-2: -The vitamins phylloquinone (K1), menadione (K3) and various menaquinones (K2) were compared for their ability to serve as a cofactor for the hepatic vitamin K-dependent carboxylase.

Detailed explanation-3: -Vitamin K3 (2-methyl-1, 4-naphthoquinone), also known as menadione, is one such naturally occurring napthoquinone in the body which is necessary for the production of prothrombin and five other blood clotting factors in humans (7).

Detailed explanation-4: -Menadione is a natural organic compound with the formula C6H4(CO)2C2H(CH3). It is an analog of 1, 4-naphthoquinone with a methyl group in the 2-position. It is sometimes called vitamin K3. Use is allowed as a nutritional supplement in animal feed because of its vitamin K activity.