BIOMOLECULES AND ENZYMES

BIOLOGY

VITAMINS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Deficiency of what two vitamins can cause megaloblastic anemia?
A
B9 and B6
B
Folic acid and Biotin
C
Cyanocobalamin and folic acid
D
B12 and B3
Explanation: 

Detailed explanation-1: -Anemias caused by a lack of vitamin B12 or a lack of folate are 2 types of megaloblastic anemia. With these types of anemia, the red blood cells don’t develop normally. They are very large. And they are shaped like an oval, not round like healthy red blood cells.

Detailed explanation-2: -Megaloblastic anemia is most often due to hypovitaminosis, specifically vitamin B12 (cobalamin) and folate deficiencies, which are necessary for the synthesis of DNA. [3] Copper deficiency and adverse drug reactions (due to drug interference with DNA synthesis) are other well-known causes of megaloblastic anemia.

Detailed explanation-3: -Low levels of folic acid can cause megaloblastic anemia. With this condition, red blood cells are larger than normal. There are fewer of these cells. They are also oval-shaped, not round.

Detailed explanation-4: -The most common causes of megaloblastic anemia are deficiency of either cobalamin (vitamin B12) or folate (vitamin B9). These two vitamins serve as building blocks and are essential for the production of healthy cells such as the precursors to red blood cells.

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