BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Several structural analogues of vitamin K, known as 4-hydroxycoumarins, have been synthesized and function as anticoagulants. The most common is warfarin (Figure 1D), also described by the term, coumadin.

Detailed explanation-2: -Vitamin K3 (Menadione; 2-methyl-1, 4-naphthoquinone) is a structural precursor of vitamins K1 and K2 which are essential for blood clotting.

Detailed explanation-3: -Abstract. Background: Vitamin K antagonists (VKAs), such as warfarin, have remained the cornerstone of oral anticoagulation therapy in the prevention and treatment of thromboembolism for more than half a century.

Detailed explanation-4: -A systemic vitamin K analog, compound 5 (Cpd 5), possesses the ability to inhibit cell growth of tumor cells. Therefore, we investigated the effect of Cpd 5 in human hepatocellular carcinoma (HCC) cell lines and evaluated its role in apoptosis. Human HCC cell lines were cultured and treated with Cpd 5.