BIOLOGY
VITAMINS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The most potent Vitamin D metabolite is
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25-Hydroxycholecalciferol
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1, 25-Dihydroxycholecalciferol
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24, 25-Dihydroxycholecalciferol
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7-Dehydrocholesterol
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Explanation:
Detailed explanation-1: -1, 25(OH)2D is the most potent metabolite of vitamin D, and mediates most of its hormonal actions. 1, 25(OH)2D is produced from 25OHD by the enzyme 25OHD-1 hydroxylase (CYP27B1).
Detailed explanation-2: -The chemical name for Vitamin D is calciferol. In humans, the most important compounds in this group are vitamin D3 (also known as cholecalciferol) and vitamin D2 (ergocalciferol).
Detailed explanation-3: -Interpretation. 1, 25-Dihydroxyvitamin D (DVHD) concentrations are low in chronic renal failure and hypoparathyroidism. DVHD concentrations are high in sarcoidosis and other granulomatous diseases, some malignancies, primary hyperparathyroidism, and physiologic hyperparathyroidism.
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