BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Current research indicates that, in large enough doses, fluoride stimulates bone formation by osteoblastic stimulation, increases bone formation earlier and to a larger extent in trabecular bone compared to cortical bone, and increases spinal bone density.

Detailed explanation-2: -Fluoride’s benefits to mineralized tissues of the teeth are well substantiated, but fluoride also plays an important role in the mineralization of bones, increasing their structural stability. Fluoride is currently being researched as a potential treatment for osteoporosis.

Detailed explanation-3: -High systemic fluoride exposures can lead to skeletal fluorosis, a condition hallmarked by osteosclerosis, ligament calcifications, and often accompanying osteoporosis, osteomalacia, or osteopenia (Christie, 1980; Wang et al., 2007).

Detailed explanation-4: -Fluoride is a trace mineral naturally found in small amounts in a variety of foods. It is most recognized for its role in preventing and reversing dental caries and building strong teeth and bones. [1] Most fluoride is absorbed in the gut and stored in bones and teeth. Unabsorbed fluoride is excreted in urine.