CLINICAL MEDICINE

MEDICINE

CARDIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Following the sudden death of his twin brother during high school football practice, a 16-year-old boys is evaluated with an echocardiogram. Results include evidence of asymmetric left ventricular and septal hypertrophy associated with anterior motion of the anterior leaflet of the mitral valve. Which of the following best describes findings on cardiac auscultation in this patient
A
A harsh early systolic murmur associated with a prominent systolic ejection click, which is most evident while the patient is squatting
B
A harsh holosystolic murmur heard best at the apex and lower left sternal border associated with a prominent ejection click
C
A harsh holosystolic murmur associated with an early decrescendo diastolic murmur heard best along the mid-lower right sternal border
D
A harsh holosystolic murmur heard best at the left lower sternal border, which decreases during assumption of the erect position
E
A harsh crescendo-decrescendo systolic murmur heart best at the apex and lower left sternal border, increases in intensity with the Valsalva maneuver
Explanation: 

Detailed explanation-1: -RESTRICTIVE CARDIOMYOPATHY Echocardiographic features include biatrial dilatation, hypertrophied ventricles with decreased compliance, initially small LV cavities, and normal to depressed systolic function.

Detailed explanation-2: -The current diagnostic criteria for HCM are an increase in LV wall thickness ≥ 15 mm in at least one myocardial segment or ≥ 13 mm for patients with a first-degree relative with confirmed HCM, in the absence of abnormal loading conditions/other causes of LVH (e.g., hypertension, valvular heart disease) [1, 17].

Detailed explanation-3: -Hypertrophic cardiomyopathy (HCM) is an inherited heart disease defined by increased left ventricular (LV) wall thickness (≥15 mm in one or more LV myocardial segments), that cannot be explained by abnormal loading conditions (1).

Detailed explanation-4: -Sudden cardiac death (SCD) in a young person is a rare but tragic occurrence.

There is 1 question to complete.