CLINICAL MEDICINE

MEDICINE

CARDIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Mark the FALSE:
A
Serum is plasma without fibrinogen
B
The most abundant hemoglobin in adults is HbA.
C
Carboxyhemoglobin increases in smokers in CO poisoning
D
All blood cells derive from a pluripotent hematopoietic stem cell or stern cell.
E
Hematopoiesis in the fetal months takes place mainly in the bone marrow of the axial bones.
Explanation: 

Detailed explanation-1: -At 10 weeks, hematopoietic progenitor cells gradually migrate from the aorta-mesonephros-gonad (AGM) region to colonize the liver, which becomes the major hematopoietic organ. Hematopoiesis shifts from foetal liver to bone marrow at 16 gestational weeks.

Detailed explanation-2: -The fetal liver is the major hematopoietic organ during development, supporting active erythro-myeloid hematopoiesis and HSC expansion.

Detailed explanation-3: -In adults, hematopoiesis occurs in the bone marrow-the central cavity of your bones. Hematopoiesis starts with hematopoietic stem cells (HSCs), proliferative and multipotent cells that are located in specialized bone marrow regions called ‘niches’.

Detailed explanation-4: -Bone Marrow. Early in fetal life, hematopoiesis begins as red blood cell precursors appear in the yolk sac at 2 weeks gestation.

There is 1 question to complete.