CLINICAL MEDICINE

MEDICINE

CARDIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Patients with Wolff-Parkinson-White syndrome:
A
have a diseased SA node, resulting in ectopic atrial pacemakers and abnormal AV nodal conduction.
B
are highly susceptible to a variety of bradycardic rhythms due to an abnormal delay at the AV node.
C
have an accessory pathway that bypasses the AV node and causes early ventricular depolarization.
D
experience independent atrial depolarization due to failure of the Bachmann bundle between the atria.
Explanation: 

Detailed explanation-1: -People with WPW syndrome have an extra electrical pathway between the atria and the ventricles, known as an “accessory pathway.” This abnormal pathway directly connects the atria and ventricles at a site other than the AV node. It can be considered a small gap in the insulation between the atria and ventricles.

Detailed explanation-2: -Accessory pathway location, anterograde or retrograde conduction, ablation success, and recurrence rate were evaluated. Results: Among 178 patients with WPW syndrome, the most frequent location of the accessory pathway was left lateral (39.3%) which had high ablation success rate (97%) and low recurrence rate (1%).

Detailed explanation-3: -Rapid ventricular rates (ventricular tachycardia or ventricular fibrillation) lead to incomplete ventricular filling, poor output, and cardiac arrest. This is why AV nodal blockers are contraindicated in patients with WPW and atrial fibrillation, which can see atrial rates up to 600bpm.

Detailed explanation-4: -Wolff-Parkinson-White (WPW) syndrome is a relatively common heart condition that causes the heart to beat abnormally fast for periods of time. The cause is an extra electrical connection in the heart. This problem with the heart is present at birth (congenital), although symptoms may not develop until later in life.

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