CLINICAL MEDICINE

Detailed explanation-1: -This is the best method for confirming an acromegaly diagnosis. During this test, your GH blood level is measured both before and after you drink a preparation of sugar (glucose). In people who don’t have acromegaly, the glucose drink typically causes the GH level to fall.

Detailed explanation-2: -An OGTT with 75 g glucose is considered the gold standard for diagnosing acromegaly.

Detailed explanation-3: -Measurement of GH after oral glucose tolerance test (OGTT) is used for the diagnosis and surveillance of acromegaly. However, there are major discrepancies between glucose-suppressed GH and plasma IGF1 as indices of biochemical activity of acromegaly in patients with relatively mild GH oversecretion.

Detailed explanation-4: -An oral glucose suppression test is done to find out if the pituitary gland is releasing too much growth hormone (GH). The pituitary gland is a small gland (about the size of a pea) in the brain. It releases hormones into the bloodstream that affect growth.

Detailed explanation-5: -IGF test. Levels of GH in the blood can change throughout the day. Oral glucose tolerance test. To confirm the diagnosis, your doctor will order an oral glucose tolerance test.