CLINICAL MEDICINE

MEDICINE

ENDOCRINOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Increased thyroid hormone decreases the levels of cholesterol, phospholipids, and triglycerides in the plasma, and increases the free fatty acids
A
TRUE
B
FALSE
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -In fact, research suggests that even slightly low levels of thyroid hormones can cause a spike in cholesterol. Thyroid hormones help your liver process blood. When your thyroid hormone levels are low, your liver processes blood more slowly, which can lead to higher levels of cholesterol in your bloodstream.

Detailed explanation-2: -Thyroid Hormone Reduces Cholesterol via a Non-LDL Receptor-Mediated Pathway-PMC.

Detailed explanation-3: -Thyroid hormone is known to play a role in regulating the synthesis, metabolism, and mobilization of lipids. In patients with overt hypothyroidism there is an increase in serum total cholesterol, low-density lipoprotein (LDL) cholesterol, apolipoprotein B, lipoprotein(a) levels, and possibly triglyceride levels.

Detailed explanation-4: -Your body needs thyroid hormones to make cholesterol and to get rid of the cholesterol it doesn’t need. When thyroid hormone levels are low (hypothyroidism), your body doesn’t break down and remove LDL cholesterol as efficiently as usual. LDL cholesterol can then build up in your blood.

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