CLINICAL MEDICINE

Detailed explanation-1: -Calcitonin is a hormone that is produced in humans by the parafollicular cells (commonly known as C-cells ) of the thyroid gland.

Detailed explanation-2: -Calcitonin is a 32 amino acid hormone secreted by the C-cells of the thyroid gland.

Detailed explanation-3: -thyroid gland produce calcitonin, which are called C cells, or parafollicular cells arise, separately from the thyroid and migrate into it during development of the embryo.

Detailed explanation-4: -The parafollicular cells secrete calcitonin whenever the plasma calcium level exceeds its normal limit. The target site for calcitonin in the bone is the osteoclast cells, thus reducing their number and action.