CLINICAL MEDICINE

Detailed explanation-1: -T and B lymphocytes are difficult to distinguish morphologically even with electron microscopy, and antibodies are generally used to make the distinction. A specific reagent, consisting of nonionic and cationic detergents, is used for leukocyte differentiation using the Sysmex automated blood analyzer.

Detailed explanation-2: -B and T cells cannot be distinguished in routinely prepared blood smears; this requires the use of immunocytology to detect cell surface markers that are specific for the different B and T cell types.

Detailed explanation-3: -These two cell types can function independently or cooperatively to defend the body against pathogens. T-lymphocytes can be distinguished from other lymphocytes like B cells and natural killer cells (NK cells) by the presence of a T cell receptor (TCR) on the cell surface.

Detailed explanation-4: -Lymphocytes are cells that circulate in your blood that are part of the immune system. There are two main types lymphocytes: T cells and B cells. B cells produce antibody molecules that can latch on and destroy invading viruses or bacteria.