CLINICAL MEDICINE

MEDICINE

HAEMATOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Low mean cell volume (MCV), high iron binding capacity and low serum ferritin level are most consistent with
A
iron deficiency anaemia.
B
B12 deficiency anaemia.
C
Folate deficiency anaemia.
D
autoimmune hemolytic anaemia.
Explanation: 

Detailed explanation-1: -Low levels of ferritin lead to iron-deficiency anemia. This means you have too few red blood cells. Iron deficiency can come from a poor diet or blood loss. Or your body may have trouble absorbing iron from food.

Detailed explanation-2: -On the complete blood count (CBC), its measure is under 80 fL while normal MCV is between 80 to 100 fL. It is commonly seen in chronic iron-deficient anemia, anemia of chronic disease, sideroblastic anemia, and thalassemias but can also occur in other conditions.

Detailed explanation-3: -Lower-than-normal TIBC may mean: Anemia due to red blood cells being destroyed too quickly ( hemolytic anemia ) Lower-than-normal level of protein in the blood (hypoproteinemia) Inflammation. Liver disease, such as cirrhosis.

Detailed explanation-4: -A total iron-binding capacity (TIBC) test measures the blood’s ability to attach itself to iron and transport it around the body. A transferrin test is similar. If you have iron deficiency anaemia (a lack of iron in your blood), your iron level will be low but your TIBC will be high.

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