CLINICAL MEDICINE

Detailed explanation-1: -8. How is smallpox spread?-Smallpox normally spreads from direct and fairly prolonged face-to-face contact with infected persons. Smallpox also can be spread through direct contact with infected bodily fluids or contaminated objects such as bedding or clothing. Indirect spread is less common.

Detailed explanation-2: -Rarely, smallpox has spread through the air in enclosed settings, such as a building (airborne route). Smallpox can be spread by humans only. Scientists have no evidence that smallpox can be spread by insects or animals.

Detailed explanation-3: -Human-to-human transmission of variola virus occurs by inhalation of large, virus-containing airborne droplets of saliva from an infected person. Infectious virus particles are released from the sloughing off of oropharyngeal lesions.

Detailed explanation-4: -Smallpox is spread through prolonged face-to-face contact via droplets expelled from the patient’s nose and mouth, usually by coughing. Smallpox may also be transmitted through contact with materials from smallpox pustules or scabs.