MEDICINE
INFECTIOUS DISEASES
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Drugs are tested on human cells and tissues only
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Drugs are tested on human cells and tissues then on live animals
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Drugs are tested on human volunteers only
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All of the above
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Detailed explanation-1: -There are three main stages of testing: Preclinical drug trials-The drugs are tested using computer models and human cells grown in the laboratory. This allows the efficacy and possible side effects to be tested. Many substances fail this test because they damage cells or do not seem to work.
Detailed explanation-2: -Mice, rabbits, guinea pigs and monkeys (non-human primates) are some of the animals used to evaluate potential candidates in preclinical in vivo experiments. The exact questions asked during preclinical research depend on the specific strategy being tested.
Detailed explanation-3: -Regulatory bodies around the world, including the U.S. Food and Drug Administration, require all potential new medicines undergo safety studies in animals before beginning clinical trials in people.
Detailed explanation-4: -There are several reasons why the use of animals is critical for biomedical research: Animals are biologically very similar to humans. In fact, mice share more than 98% DNA with us! Animals are susceptible to many of the same health problems as humans – cancer, diabetes, heart disease, etc.