CLINICAL MEDICINE

Detailed explanation-1: -At the tissue level, inflammation is characterized by redness, swelling, heat, pain, and loss of tissue function, which result from local immune, vascular and inflammatory cell responses to infection or injury [5].

Detailed explanation-2: -Your immune system sends out its first responders: inflammatory cells and cytokines (substances that stimulate more inflammatory cells). These cells begin an inflammatory response to trap bacteria and other offending agents or start healing injured tissue. The result can be pain, swelling, bruising or redness.

Detailed explanation-3: -The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged cells release chemicals including histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling.

Detailed explanation-4: -Inflammation is part of the body’s defense mechanism. It is the process by which the immune system recognizes and removes harmful and foreign stimuli and begins the healing process. Inflammation can be either acute or chronic.[1][2][3] Acute Inflammation.

Detailed explanation-5: -The swelling process, also known as edema, is the result of acute inflammation, a response triggered by damage to living tissues. In the case of injury, the purpose of the inflammatory response is to remove components of damaged tissue in order to allow the body to begin to heal.