CLINICAL MEDICINE

MEDICINE

INFECTIOUS DISEASES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What could cause an outbreak of malaria in a country after it had been eliminated?1 mosquitoes become resistant to insecticides2 migration of population due to war3 malarial parasites become resistant to quinine (the medicine for malaria)
A
1, 2 and 3
B
1 and 3 only
C
2 and 3 only
D
1 and 2 only
Explanation: 

Detailed explanation-1: -Usually, people get malaria by being bitten by an infective female Anopheles mosquito. Only Anopheles mosquitoes can transmit malaria and they must have been infected through a previous blood meal taken from an infected person.

Detailed explanation-2: -High-level pyrimethamine resistance results from the accumulation of mutations in the dhfr domain of pfdhfr-ts, principally at codons 108, 59 and 51, where the most common allelic variants encode S108N, N51I and C59R.

Detailed explanation-3: -The malaria epidemic of 79 AD devastated the fertile, marshy croplands surrounding the city, causing local farmers to abandon their fields and villages.

Detailed explanation-4: -From mother to unborn child. Through blood transfusions. By sharing needles used to inject drugs. 09-Feb-2023

There is 1 question to complete.