A 27 year old woman, G1POAO, 20 weeks pregnant was brought to the hospital with complaints of fever since 1 week ago. Complaints accompanied by palpitations and often restless. On physical examination found blood pressure 140/80 mmHg, pulse 140 x/minute, temperature 39$^circ$C. On physical examination of the neck, a palpable thyroid was found to be the size of a thumb, fine tremors were also found in the palms. The doctor gives methimazole to the patient, the mechanism of the drug is?

NEPHROLOGY

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A 27 year old woman, G1POAO, 20 weeks pregnant was brought to the hospital with complaints of fever since 1 week ago. Complaints accompanied by palpitations and often restless. On physical examination found blood pressure 140/80 mmHg, pulse 140 x/minute, temperature 39

A	Inhibits iodine trapping/uptake by thyroid cells
B	Inhibits synthesis of T3 and T4 hormones
C	Inhibits the secretion of T3 and T4 hormones by thyroid gland cells
D	Reduces the vascularity of the thyroid gland
E	Inhibits the secretion of the hormone TSH

Explanation:

Detailed explanation-1: -During pregnancy, the amount of blood in your body increases significantly. Your heart works harder to pump the extra blood throughout your body and to the fetus. This extra work can result in heart palpitations. Although they can be alarming, most pregnancy heart palpitations aren’t dangerous.

Detailed explanation-2: -While most of the time palpitations aren’t a cause for worry, in a small percentage of women, they could be a sign of something more serious. Call your doctor or go to the emergency if: The palpitations are lasting longer or getting worse. You also feel dizzy, lightheaded, or feeling faint.

Detailed explanation-3: -During pregnancy, the amount of blood pumped by the heart (cardiac output) increases by 30 to 50%. As cardiac output increases, the heart rate at rest speeds up from a normal prepregnancy rate of about 70 beats per minute to as high as 90 beats per minute.

Detailed explanation-4: -A normal heart rate for a fetus can range from 110 to 160 beats per minute (BPM). Very early in pregnancy, it is typically around 110 BPM. Fetal heart rate may speed up to 140 to 170 BPM around the ninth week and slow to around 110 to 160 BPM thereafter.

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CLINICAL MEDICINE

MEDICINE

NEPHROLOGY