CLINICAL MEDICINE

Detailed explanation-1: -Multi-infarct dementia (MID) is a common cause of memory loss in older people. MID is caused by multiple strokes (disruption of blood flow to the brain) which lead to damaged brain tissue. Some strokes may occur without noticeable symptoms; doctors may refer to these as “silent strokes.”

Detailed explanation-2: -CADASIL (cerebral autosomal dominant arteriopathy with sub-cortical infarcts and leukoencephalopathy) is a genetic disorder that generally leads to dementia of the vascular type. One parent with the gene for CADASIL passes it on to a child, which makes it an autosomal-dominant inheritance disorder.

Detailed explanation-3: -Vascular dementia is caused by a series of small strokes. A stroke is a disturbance in or blockage of the blood supply to any part of the brain. A stroke is also called an infarct. Multi-infarct means that more than one area in the brain has been injured due to a lack of blood.

Detailed explanation-4: -People with this type of VaD, sometimes called multi-infarct dementia, have a so-called “stepwise” progression of their symptoms, meaning that their symptoms stay the same for a while and then suddenly get worse. This can be a challenge for caregivers.