MEDICINE
ONCOLOGY
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Adenocarcinoma is the least frequent and is associated with hypertrophic osteorathropathies.
|
|
|
Epidermoid is associated with the Pancoast tumor, located at the base of the lungs, and may present with Horner’s syndrome.
|
|
|
Small cell cancer is the deadliest and may be associated with superior vena cava syndrome
|
|
|
Anaplastic is not associated with gynecomastia or cavitations
|
Detailed explanation-1: -Lung cancer and non-Hodgkin lymphoma (NHL) are responsible for 85% of malignancy-related SVCS cases. Small cell lung cancer (SCLC) and squamous cell carcinoma are the two most frequent lung cancer histologic types associated with SVCS.
Detailed explanation-2: -Superior vena cava syndrome (SVCS) happens when the superior vena cava is partially blocked or compressed. Cancer is usually the main cause of SVCS.
Detailed explanation-3: -SVC syndrome is more common in small cell lung cancer, occurring in approximately 10% of cases [6]. Other extrinsic etiologies of SVC syndrome include lymphoma and metastatic disease, as well as nonmalignant causes, including aortic aneurysm [7, 8].
Detailed explanation-4: -The characteristic physical findings of SVCS include venous distention of the neck and chest wall, facial edema, upper-extremity edema, mental changes, plethora, cyanosis, papilledema, stupor, and even coma. Bending forward or lying down may aggravate the symptoms and signs.