CLINICAL MEDICINE

MEDICINE

ONCOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Based on the TNM classification for lung cancer, what does N2 mean?
A
Peribronchial or hilar node(s)
B
Contralateral and/or extrathoracic mediastinal node(s)
C
Ipsilateral and contralateral mediastinal node(s)
D
Ganglion(is) a novel mediastinal ipsilateral
Explanation: 

Detailed explanation-1: -Ipsilateral mediastinal metastatic adenopathy, including upper, aortico-pulmonary and lower mediastinum, and subcarinal nodes, is considered as N2.

Detailed explanation-2: -Mediastinal lymph node involvement is one of the most important prognostic factors in non-small-cell lung cancer (NSCLC). N2 disease is defined as ipsilateral mediastinal lymph node metastasis. This affection not only influences in the prognosis of the patient, but also in the therapeutic options of treatment.

Detailed explanation-3: -These lymph nodes are on the same side as the main lung tumor (N2). The cancer has not spread to distant parts of the body (M0). The tumor has one or more of the following features (T2): It is larger than 3 cm but not larger than 5 cm across.

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