CLINICAL MEDICINE

Detailed explanation-1: -ICE chemotherapy refers to a chemotherapy regimen that includes ifosfamide, carboplatin, and etoposide. Doctors often prescribe this treatment for people with Hodgkin lymphoma and non-Hodgkin lymphoma that has come back. Many individuals who undergo ICE chemotherapy also have a stem cell transplant.

Detailed explanation-2: -An abbreviation for a chemotherapy combination that is used to treat non-Hodgkin and Hodgkin lymphomas that have come back and do not respond to other treatments. It includes the drugs ifosfamide, carboplatin, and etoposide phosphate. Also called ICE.

Detailed explanation-3: -Carboplatin and etoposide are chemotherapy drugs you have together. You might have them as a treatment for a number of different cancer types. Find out more about the treatment for your cancer type.

Detailed explanation-4: -Drug type: Etoposide is an anti-cancer ("antineoplastic” or “cytotoxic") chemotherapy drug. This medication is classified as a “plant alkaloid” and “topoisomerase II inhibitor.” (For more detail, see “How this drug works” section below).

Detailed explanation-5: -Treatment. ICE chemotherapy consisted of ifosfamide (1, 500 mg/m2, days 1–4), carboplatin (100 mg/m2, days 1–4), and etoposide (150 mg/m2, days 1–4).