CLINICAL MEDICINE

Detailed explanation-1: -Abstract. The term “epigenetics” was introduced in 1942 by embryologist Conrad Waddington, who, relating it to the 17th century concept of “epigenesis", defined it as the complex of developmental processes between the genotype and phenotype.

Detailed explanation-2: -Waddington introduced the term epigenetics in 1942 (Waddington, 1942) as a refinement of his conception of an “epigenetic landscape” (Waddington, 1940).

Detailed explanation-3: -This realization was fundamental to Waddington’s concept of epigenetics. In 1958, 16 years after Waddington first coined the term, David Nanney published a paper in which he used the term epigenetics to distinguish between different types of cellular control systems.

Detailed explanation-4: -Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work. Unlike genetic changes, epigenetic changes are reversible and do not change your DNA sequence, but they can change how your body reads a DNA sequence.