2016
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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FOXF1
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FOXE2
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FOXC2
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FOXF2
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Detailed explanation-1: -These genes are called: amyloid precursor protein (APP) presenilin 1 (PSEN1) presenilin 2 (PSEN2).
Detailed explanation-2: -Certain genes can increase the risk of developing dementia, including Alzheimer’s disease. One of the most significant genetic risk factors is a form of the apolipoprotein E gene called APOE4. About 25% of people carry one copy of APOE4, and 2 to 3% carry two copies.
Detailed explanation-3: -Phosphodiesterase 4D (PDE4D) PDE4D, which had previously been identified through GWAs, was identified as the first novel gene to predispose to ischemic stroke independently of conventional risk factors.
Detailed explanation-4: -The most common gene associated with late-onset Alzheimer’s disease is a risk gene called apolipoprotein E (APOE). APOE has three common forms: APOE e2-the least common-reduces the risk of Alzheimer’s.
Detailed explanation-5: -The majority of dementia is not inherited by children and grandchildren. In rarer types of dementia there may be a strong genetic link, but these are only a tiny proportion of overall cases of dementia.