EVERYDAY SCIENCE

Detailed explanation-1: -During the process of splicing, introns are removed from the pre-mRNA by the spliceosome and exons are spliced back together. If the introns are not removed, the RNA would be translated into a nonfunctional protein.

Detailed explanation-2: -One end of the intron is cut and folded back on itself to join and form a loop. The spliceosome then cuts the RNA to release the loop and join the two exons together. The edited RNA and intron are released and the spliceosome disassembles. This process is repeated for every intron in the RNA.

Detailed explanation-3: -Introns are removed from the pre-mRNA by the activity of a complex called the spliceosome. The spliceosome is made up of proteins and small RNAs that are associated to form protein-RNA enzymes called small nuclear ribonucleoproteins or snRNPs (pronounced SNURPS).

Detailed explanation-4: -Mutations in the Spliceosome Machinery Spliceosomes are complexes composed of small nuclear RNA (snRNA) that remove introns in protein-encoding genes.