OBJECTIVE LIFE SCIENCE
BIOCHEMISTRY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Gly
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Ser
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Glu
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Tyr
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Asn
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Detailed explanation-1: -Protein Modifications | Mucin Family of Glycoproteins☆ N-linked oligosaccharides are attached via a GlcNAc linkage to the side chain nitrogen of Asn in the consensus sequence NXT/S (X ≠ P) known as the “glycosylation sequon”.
Detailed explanation-2: -N-Glycosylation is an essential protein modification that affects a multitude of cellular functions. The attachment of oligosaccharides chains occurs on Asn residue in proteins, within a typical Asn-X-Ser/Thr sequence, where X is any amino acid except for proline (5, 6).
Detailed explanation-3: -In N-linked glycosylation, the glycan is attached to the amide nitrogen of asparagine (N). More specifically, N-linked glycosylation predominantly occurs in N-X-S/T (S: serine, T: threonine) sequons, and in some rare cases N-X-C (C: cysteine), where X can be any amino acid except proline7.